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Updated: Feb 22, 2026

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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非酸化ペントースリン酸経路は,NADPHの恒常性を維持することによって,CD8+ T細胞免疫を調節する

Jingyu Feng1, Qian Zhang1,2, Li Luo3

  • 1Department of Pathology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Proceedings of the National Academy of Sciences of the United States of America
|February 20, 2026
PubMed
まとめ

非酸化ペントースリン酸塩経路 (non-oxPPP) は,CD8+T細胞機能に不可欠であり,免疫応答のNADPHホメオスタシスをサポートします. ノン-オックスPPPの増強はT細胞の記憶とエフェクター機能を高め,がんの免疫療法に潜在力を提供します.

キーワード:
CD8+ T細胞によるCD8+ T細胞によるNADPHとNADPHを組み合わせたものです.メモリーT細胞のT細胞は,非酸化ペントース・リン酸経路である.

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