関連する実験動画

Updated: Feb 22, 2026

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis
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CRISPR/Cas12aベースのmiRNA解析におけるカスケード増幅のためのSDAを調整する構造主導CHA変異.

Fei Yu1, Dan Yue1, Fanting Wang1

  • 1College of Public Health, Zhengzhou University, Zhengzhou, Henan, 450001, China.

Talanta
|February 20, 2026
PubMed
まとめ

この研究は,高感度CRISPR/Cas12aベースのマイクロRNA検出のために,触媒式ヘアピンアセンブリ (VCHA) と鎖移位増幅 (SDA) を組み合わせた新しいバイオセンシングプラットフォームを導入しています. このプラットフォームは,腫瘍バイオマーカーに対する超低検出限界を達成しています.

キーワード:
CRISPRCas12aは,CRISPRCas12aとして使用されています.マルチ信号の増幅が多発しています.ストランドシプレッシャー増幅 (SDA)触媒式ヘアピンアセンブリ (VCHA) の変種.miRNARNAはミクロRNAである

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