周期性嘔吐症候群 (Cyclic vomiting syndrome) とは,循環性嘔吐症候群 (Cyclic vomiting syndrome) とは,循環性嘔吐症候群 (Cyclic vomiting syndrome)
1Department of Pediatrics, Teikyo University School of Medicine, Itabashi-Ku, Tokyo, Japan.
Brain & development
|February 20, 2026
まとめ
周期性嘔吐症候群 (CVS) は診断が困難で,症状の発症と診断の間の遅延が著しい. 現在のガイドラインでは,様々な急性および予防的治療が提案されていますが,さらなる研究が必要です.
科学分野:
- 小児胃腸内科 小児胃腸内科
- 神経学 神経学とは
背景:
- 周期性嘔吐症候群 (CVS) は,小児における再発性嘔吐エピソードとして現れる.
- CVSの診断はしばしば遅れており,症状の発症と診断の間の平均は2.3年です.
- CVSの罹患率は0.3%から2%です.
研究 の 目的:
- CVSの病理生理学,予後,および自然史を調査する.
- CVS管理のための現在の治療戦略をレビューする.
- 北米小児胃腸病,肝臓病,栄養学会 (NASPGHAN) 2025年ガイドラインの勧告を強調する.
主な方法:
- CVSに関する既存の文献と臨床データのレビュー.
- 小児CVS症例における診断の遅延と症状の発症の分析.
- CVS治療のためのNASPGHAN 2025ガイドラインの勧告をまとめました.
主要な成果:
- 症状の発症の平均年齢は5.7歳であり,CVSの子供の診断は8.0歳でした.
- CVSに対する中絶療法に関するランダム化対照試験は実施されていません.
- NASPGHAN 2025のガイドラインは,特定の急性および予防薬剤を推奨し,特定の抗発作薬に対して警告しています.
結論:
- 子どものCVSの診断は困難であり,その根本的なメカニズムと長期的な結果に関するさらなる研究が必要である.
- 現在の治療アプローチには,既定の小児ガイドラインに従って,急性エピソードと予防のための一連の薬が含まれています.
- 抗発作薬は,他の治療法に反応しない重症で耐性のある症例に限られています.
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