犬におけるオステオサルコマを示唆する転移性差分サルコマによる3度目の心房静脈閉塞
K E Moy-Trigilio1, H R Coffin2, R P Taylor2
1Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
まとめ
犬のサルコマは3度目の心房静脈閉塞を引き起こし,麻痺や食欲不振を引き起こした. 解剖は多焦点性腫瘍病変を明らかにし,彼の病理学はオステオサルコマを優先した.
科学分野:
- 獣医学病理学 獣医学病理学について
- 犬の腫瘍学について
- 心血管病理学 心血管病理学
背景:
- 9歳の犬は,重度の怠惰,食欲低下,ブラディカルディアを呈した.
- 臨床的兆候は,重大な心臓の妥協を示唆しました.
研究 の 目的:
- 犬の患者における第3度の心房動脈 (AV) 阻害および関連する臨床症状の原因を調査する.
- 診断評価と解剖で特定された腫瘍病変の性質と範囲を特徴付けるため.
主な方法:
- 身体検査,診断イメージング,および臨床病理学的評価を含む診断評価.
- 遺体解剖と感染した組織の総合的な組織病理学的検査.
- 形態学的特徴に基づいてサルコマサブタイプの優先順位付け.
主要な成果:
- 3度目の AV ブロックが診断され,隔膜 AV 交差点領域の浸透性質に起因しました.
- 多焦点性腫瘍病変は,心周,心筋,AV結路,肋骨,腎臓,臓,中腸で確認されました.
- 組織病理学では,差異性の低いサルコマを明らかにし,オステオサルコマの特徴を示唆した.
結論:
- オステオサルコマ原発の可能性がある差異性の悪質なサルコマが,犬の心臓および全身疾患の主な原因でした.
- サルコマの多焦点拡散は,臓器の広範な関与につながり,致命的な結果に寄与しました.
- このケースは,犬におけるAVブロックの微分診断において,攻撃的,転移性腫瘍を考慮することの重要性を強調しています.
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