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Updated: Feb 22, 2026

A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas
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A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas

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細胞フリーゲノミクスは,Mycobacterium tuberculosisの転写サイクルの基本的規制原理を明らかにしています

Ruby Froom1, Michael B Wolfe2, Kelly N Eckartt3

  • 1Laboratory of Molecular Pathogenesis, The Rockefeller University, New York, NY 10065, USA; Laboratory of Host-Pathogen Biology, The Rockefeller University, New York, NY 10065, USA.

Molecular cell
|February 20, 2026
PubMed
まとめ

細胞フリーゲノミクス (CFG) は,複雑な微生物における遺伝子調節のゲノムスケール分析を可能にします. この新しい方法は,直接的な転写因子標的を特定し,細胞転写に関する理解を深める.

キーワード:
ミコバクテリウム結核菌 (Mycobacterium tuberculosis) が感染している.RNAポリメラーゼによるRNAポリメラーゼは,細胞フリーゲノミクスゲノムスケールトランスクリプショントランスクリプション・ファクタートランスクリプション規制

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