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Updated: Feb 22, 2026

Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis
09:44

Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis

Published on: June 13, 2021

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輸入国として輸出国Mdr1は,薬剤耐性カンジダ菌と闘うためのアキレス・ヒールです

Jinyao Chen1, Ming Zhang2, Yeji Wang1

  • 1Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Cell chemical biology
|February 20, 2026
PubMed
まとめ

薬剤耐性を克服するために,研究者は,抗真菌薬の輸出者を輸入者に改造しました. 彼らはMKT-077を発見し,Mdr1の輸出者を輸入者として利用することで,耐性のあるCandida albicansを標的にする化合物を発見し,治療の可能性を示しました.

キーワード:
カンジダ (Candida) とはアゾール耐性である.シアニンの誘導体である.麻薬の輸入者,麻薬の輸入者エフフックスポンプはエフフックスポンプです.

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