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Updated: Feb 22, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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転写因子SPI1は,免疫抑制性CD45+のエリトロイド原始細胞を駆動して,リウマチ性関節炎を緩和する

Wei-Hang Zhu1, Man-Li Wang1, Xia Meng1

  • 1Department of Rheumatology and Immunology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

RMD open
|February 20, 2026
PubMed
まとめ

CD45+赤色素原始細胞 (EPC) は,関節リウマチ症 (RA) で拡張され,SPI1/TGF-βシグナル伝達を通じてマクロファージを調節することによって炎症を抑制します. これらの細胞は,RA治療の新たな治療標的を代表しています.

キーワード:
関節炎,リウマチなどです.自己免疫疾患は,自己免疫疾患である.サイトカイン (cytokine) とは

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