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Updated: Feb 22, 2026

Correlating Gene-specific DNA Methylation Changes with Expression and Transcriptional Activity of Astrocytic KCNJ10 Kir4.1
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Correlating Gene-specific DNA Methylation Changes with Expression and Transcriptional Activity of Astrocytic KCNJ10 Kir4.1

Published on: September 26, 2015

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統合失調症におけるCSFと血液におけるシナプス遺伝子の差異的なDNAメチル化

Kirsten Jahn1, Adrian Groh2, Ole Riemer2

  • 1Laboratory of Molecular Neurosciences (LMN), Dept. of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany. Jahn.Kirsten@mh-hannover.de.

Schizophrenia (Heidelberg, Germany)
|February 20, 2026
PubMed
まとめ

統合失調症 (統合失調症) のエピジェネティックの変化はシナプス遺伝子に影響します. ドーパミントランスポーター (DAT) のDNAメチル化は,SZ患者において低かったが,シナプス後密度タンパク質95 (PSD95) のメチル化は,彼らの脳脊髄液において高かった.

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