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Updated: Feb 23, 2026

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アミロイド標的免疫療法に適格となる患者数が少ない

Frank Jessen1

  • 1Department of Psychiatry, University of Cologne, Medical Faculty, Kerpener Strasse 62, 50937 Cologne, Germany; German Center for Neurodegenerative Diseases (DZNE), Germany; European Alzheimer's Disease Consortium (EADC).

The journal of prevention of Alzheimer's disease
|February 21, 2026
PubMed
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No abstract available in PubMed .

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
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