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Updated: May 2, 2026

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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VDAC1依存型mtDNAの放出をターゲットにすることで,線維芽細胞の先天性免疫活性化と白病原生を弱める

Jinpeng Lv1, Huansha Zhang1, Wenhao Yu1

  • 1Jiangsu Provincial Engineering Research Center for Drug Intelligent Manufacturing and Precision Delivery, School of Pharmacy, Changzhou University, Changzhou 213000, China.

International immunopharmacology
|February 21, 2026
PubMed
まとめ

白症における酸化ストレスは,ミトコンドリアDNAの放出を通じて皮膚線維芽細胞を活性化し,炎症を誘発する. VDAC1のオリゴメリゼーションを阻害することは,白症の治療のための潜在的な治療戦略を提供します.

キーワード:
皮膚の線維芽細胞が形成される.オキシダティブ・ストレスは,VDAC1 オリゴメリゼーションVitiligo (ビチリゴ) とはcGAS-STING経路についてmtDNAの放出によって,

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