内視鏡室でのC. difficileを防ぐための保護バリアの封じ込め:将来的な,病院ベースの介入研究
Quan Wen1, Sheng Zhang1, Yanfeng Zhao2
1Department of Microbiota Medicine & Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China.; Key Lab of Holistic Integrative Enterology, Jiangsu Engineering Research Center for Advanced Microbiota Medicine, Nanjing Medical University, Nanjing, 210011, Jiangsu, China.
まとめ
新しい研究では,単回使用のフルベッド・プロテクティブ・バリア・コンテインメント (PBC) を使用すると,内視鏡室の表面におけるClostridioides difficileの汚染を大幅に減らすことが示されています. この介入は,クロストリディオイドス・ディフィシル感染 (CDI) の発生率を低下させました.
科学分野:
- 感染症対策対策の対策です.
- ヘルスケア関連感染症
- クリニカル・マイクロバイオロジー
背景:
- エンドスコピーの部屋のハイタッチ表面は,Clostridioides difficile.に汚染されることがあります.
- これらの環境でクロストリディオイドス・ディフィシル感染 (CDI) の伝播を防ぐために,効果的な戦略が必要である.
研究 の 目的:
- 中国の内視鏡室の高接触面でのClostridioides difficileの汚染を調査する.
- 保護バリア・コンテインメント (PBC) を用いた標的介入がCDI率に与える影響を評価する.
主な方法:
- 中国の3つの高等病院を対象とした前向きな研究.
- リアルタイムPCRは,移転ベッド,治療カート,内視鏡ホスト,およびコンピュータの周辺機器のClostridioides difficileを検出するために使用されました.
- 1つのセンターで1回使用のフルベッドPBC介入が実施されました.
主要な成果:
- 全体的な汚染率は6.5%で,移転ベッドは17.2%でした.
- PBCの実施後,移転床の汚染は0% (p=0.043) に減少した.
- CDIの発生率は1000患者日当たり0.15から0.10に減少した (p=0.009),大幅なコスト削減が予測されている.
結論:
- 一回使用のフルベッドPBCは,Clostridioides difficileの汚染とCDIの発生率を減らすのに有効です.
- この介入は,内視鏡の設定のための実用的で費用対効果の高い感染制御ソリューションを提供します.
関連する概念動画
01:17Transmission-based Precautions I: Contact, Enteric, and Droplets
4.8K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
4.8K
01:22Healthcare Associated Infections II: Preventive Measures
4.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.4K
01:25Transmission-based Precautions II: Airborne and Protective Environment
2.0K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
2.0K
01:26Standard Precaution
3.2K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
3.2K
01:30Cleaning, Sterilization, and Disinfection
10.9K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
10.9K
01:18Surface Membrane Barriers
3.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
3.1K