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Updated: Feb 23, 2026

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
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Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy

Published on: January 31, 2025

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カドミウムによって誘発されたATP6V0A1の不安定化は,リンソソームの機能を低下させ,肝臓の脂質ホメオスタシスを破壊する

Juan Huo1, Kongdong Li2, Haifeng Shi2

  • 1Department of Central Laboratory, the First People's Hospital of Lianyungang, Lianyungang, Jiangsu, 222002, China.

Biochimica et biophysica acta. Molecular and cell biology of lipids
|February 21, 2026
PubMed
まとめ

慢性的なカドミウム曝露は,ATP6V0A1タンパク質を分解し,リソソーム機能を低下させ,オートファギーを阻害することにより,高トリグリセリデミアを引き起こす. ATP6V0A1レベルを回復することで,脂質代謝を正常化し,カドミウム誘発性脂肪肝疾患を治療することができます.

キーワード:
ATP6V0A1 を使ったものです.オートファギー (自食) とはカドミウム カドミウム肝臓 肝臓 肝臓 肝臓ライソソームはライソソームである.トリグリセリドはトリグリセリドである.

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