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Updated: Feb 23, 2026

Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice
07:07

Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice

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エクストラフォリキュラーTph2-CD11c+CD21- B細胞の相互作用は,IgG4に関連する疾患における免疫不調をオーケストラ化する

Hiroshi Sakamoto1, Ryuta Kamekura2, Shin Takayanagi1

  • 1Department of Otolaryngology and Head and Neck Surgery, Sapporo Medical University School of Medicine, Chuo-ku, Sapporo, Japan.

Allergology international : official journal of the Japanese Society of Allergology
|February 21, 2026
PubMed
まとめ

新しいTph2およびCD11c+CD21-B細胞軸は,IgG4関連の疾患 (IgG4-RD) を駆動する. この軸は,免疫細胞とIgG4の産生を結びつけ,ステロイド以外のIgG4-RDの新たな治療法を提供している.

キーワード:
CD11c (((+)) CD21 (((-) B細胞についてエクトピックリンパ性構造の外部リンパ性構造集団外免疫反応は,集団外免疫反応として生じる.IgG4に関連する疾患周辺Tヘルパー2 (Tph2) 細胞

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