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Updated: Feb 23, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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ASOビジュアルアブストラクト：パラダイムシフト：cT4およびcN2結腸がんに対する術前化学療法の利用と転帰

Bennett W Hartley1, Vivi W Chen2, Punam Amin2

  • 1Department of Surgery, Baylor College of Medicine, Houston, TX, USA. bennett.hartley@bcm.edu.

Annals of surgical oncology
|February 21, 2026
PubMed
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No abstract available in PubMed .

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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