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Updated: Feb 23, 2026

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice
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精神医学における全静的負荷:体系的なレビューとメタ解析

Sabine Finlay1,2,3, Riana Marie1,2,4, Donna Rudd3

  • 1Laboratory of Psychiatric Neuroscience, Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, Queensland, Australia.

Stress (Amsterdam, Netherlands)
|February 21, 2026
PubMed
まとめ

アロスタティック・ロード (AL) モデルでは,精神疾患,特に統合失調症と精神病においてALが上昇していることが示されています. メジャーうつ病は,健康な対照群と比較して有意なALの違いを示さなかった.

キーワード:
精神疾患 精神疾患とはアロスタティック負荷による全静的負荷バイオマーカー バイオマーカーメンタルヘルス メンタルヘルスメタアナリシスのメタ分析システミック・ディズレギュレーション

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The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
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The shearing force, possessing potential directionality within the plane of the section, is simplified into two component forces running parallel to the x and y axes....
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