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Updated: Feb 24, 2026

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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CRISPR-SpyCas9をAcrIIA26によって抑制する分子メカニズム

Ziqi Zhen1, Ling Yu1, Yuwei Zhu1

  • 1HIT Center for Life Sciences, School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150080, China.

Biochemical and biophysical research communications
|February 22, 2026
PubMed
まとめ

新しい抗CRISPRタンパク質であるAcrIIA26は,DNA結合を阻害することによって,Streptococcus pyogenes Cas9 (SpyCas9) を抑制する. sgRNA独立のメカニズムは,拡張された遺伝子編集制御を可能にします.

キーワード:
AcrIIA2626 アクリリアクリオ・エム・エム (Cryo-EM) とはスパイキャス9アンチ・クリスプリル.

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