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Updated: Feb 24, 2026

Single-cell RNA Sequencing and Analysis of Human Pancreatic Islets
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GWASと単細胞トランスクリプトーム分析を通じて,タイプ1糖尿病に関する性別特異的なゲノム洞察

Hui-Qi Qu1, Kayleigh Ostberg1, Diana J Slater1

  • 1The Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

Diabetes research and clinical practice
|February 22, 2026
PubMed
まとめ

性別分層化された全ゲノム関連研究 (GWAS) は,男性と女性に特有の新しい1型糖尿病 (T1D) 遺伝的リスク要因を明らかにしています. 性別特異ポリジェニックリスクスコア (PRS) は,標準PRSと比較してT1Dリスク予測を大幅に改善します.

キーワード:
微分式は,微分式で表現する.GWAS GWASは,GWASと呼ばれるものです.周辺血液の単核細胞は,周辺血液の単核細胞である.ポリジェネティックリスクスコア ポリジェネティックリスクスコア性別の違い 性別の違い1型糖尿病は1型糖尿病である.単細胞RNAシーケンシング

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