Search research articles

お問い合わせ

JoVEについて

概要リーダーシップブログ JoVEヘルプセンター

著者向け

出版プロセス編集委員会範囲と方針査読よくある質問投稿

図書館員向け

推薦の声購読アクセスリソース図書館諮問委員会よくある質問

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments アーカイブ

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教員リソースセンター教員サイト

プライバシーポリシー

関連する概念動画

Probability Laws

Probability Laws

Pedigree Analysis

Pedigree Analysis

Hardy-Weinberg Principle

Hardy-Weinberg Principle

Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.

Trihybrid Crosses

Trihybrid Crosses

Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...

Punnett Squares

Punnett Squares

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for k_a Estimation

This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え

Same author

Tuneable structural and environmental factors for stability of rosette nanotubes.

Nanoscale advances·2026

Same author

Comparison of genetic heat tolerance in Japanese Holstein cows estimated by using milk yield, somatic cell score, or milk β-hydroxybutyrate.

Journal of dairy science·2026

Same author

Physical Function Indicators Associated with Reduced Work Productivity and Estimated Economic Loss in Employed Patients with Respiratory Diseases.

Journal of occupational and environmental medicine·2026

Same author

Computing inbreeding coefficients accounting for unknown parents using pedigree-based metafounders.

JDS communications·2026

Same author

Peptide-Functionalized Rosette Nanotubes: Programmable Supramolecular Assembly and Tunable Peptide Surface Organization.

Biomacromolecules·2026

Same author

Insulin-like growth factor-1 regulates vascular endothelial growth factor synthesis and secretion in mammary epithelial cells.

Bioscience, biotechnology, and biochemistry·2026

Same journal

The mitogenome diversity of Alpine Rendena cattle: new clues on its maternal origin and the complex substructure of haplogroup T3.

Genetics, selection, evolution : GSE·2026

Same journal

Genomic partitioning and functional dissection of inbreeding depression for stature in Brown Swiss cattle.

Genetics, selection, evolution : GSE·2026

Same journal

Modest contribution of metabolomic data to genomic prediction of breeding values for feed conversion ratio in pigs.

Genetics, selection, evolution : GSE·2026

Same journal

Determining crossover count and position in two pig lines with different selection histories.

Genetics, selection, evolution : GSE·2026

Same journal

Effect of methylation on genome mutability in cattle.

Genetics, selection, evolution : GSE·2026

Same journal

Genomic selection strategies and their potential to maintain rare alleles and de-novo mutations: a long-term assessment.

Genetics, selection, evolution : GSE·2026

関連記事をすべて見る

Search research articles

関連する実験動画

Updated: Feb 24, 2026

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Published on: October 5, 2018

インブリーディング係数を計算するための修正された間接的な方法.

Che Hsuan Huang¹, Seijiro Hirama², Toshimi Baba³

¹Division of Dairy Production Research, Hokkaido Agricultural Research Center, NARO, Sapporo, 062-8555, Japan.

Genetics, selection, evolution : GSE

|February 22, 2026

まとめ

この要約は機械生成です。

新しい間接的な方法により,大型家畜の繁殖係数の計算が大幅に高速化されています. この強化されたアルゴリズムは効率を向上させ,人工授精の育種プログラムに実用的です.

さらに関連する動画

Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella

Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella

Published on: May 13, 2019

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Published on: July 6, 2022

関連する実験動画

Last Updated: Feb 24, 2026

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Published on: October 5, 2018

Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella

Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella

Published on: May 13, 2019

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Published on: July 6, 2022

科学分野:

動物遺伝学動物遺伝学
定量遺伝学定量遺伝学とは
コンピュータ生物学コンピュータ生物学

背景:

インブリーディング係数を計算するための既存の方法は,メモリ使用,系統の深さ,および家族の大きさに関する制限に直面しています.
これらの制限は,大規模な家畜集団における効率的な計算を妨げます.

研究の目的:

インブリーディング係数を効率的に計算するための修正された間接的な方法を提示する.
大規模な系統と深い祖先情報によって引き起こされる計算上の課題に対処するために.

主な方法:

インブリーディング係数の計算に必要な要素を識別,計算,保存するための修正された間接アルゴリズムの開発.
広範な血統情報を持つ860万の日本のホルシュタインの大規模なデータセットでアルゴリズムのテスト.

主要な成果:

修正された間接的な方法は,以前の間接的な方法と比較して,計算時間を103.4秒から7.2秒に大幅に短縮しました.
32スレッドの並列化により,計算時間はさらに1.1秒に短縮されました.
この方法は,系統の深さや家族の大きさの変動に対して堅実性を示しました.

結論:

提案された修正された間接的な方法は,同胞繁殖係数を計算するための重要な計算上の改善を提供します.
効率性とスケーラビリティにより,大型家畜の管理,特に人工授精を使用する家畜の管理に非常に実用的です.