関連する実験動画

Updated: Feb 24, 2026

LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics
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LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics

Published on: April 9, 2017

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コンピュータで設計されたミニタンパク質で,難解なイソアスパルテートへのデアミデーションとイソメリゼーション

Katerina M Blejec1, Colin A Smith1

  • 1Department of Chemistry, Wesleyan University, Middletown, Connecticut, USA.

Protein science : a publication of the Protein Society
|February 22, 2026
PubMed
まとめ

計算によるタンパク質設計は,治療のための新しいミニタンパク質を作成します. 研究者は,NMRを用いてデアミデーションを研究し,イソアスパルテート製品が動態的に好ましいことを発見し,ミニタンパク質の安定性と治療の可能性に影響を与えました.

キーワード:
NMR化学シフトの乱れ,NMR化学シフトの乱れNMRの運動学についてアスパラジンのデアミデーションアスパルテートのイソメリゼーションミニプロテイン ミニプロテインタンパク質のデザインタンパク質の安定性

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