脳卒中患者の認知機能に対する経頭蓋磁気刺激と回想法の併用療法の潜在的利点
1Rehabilitation Treatment Center, Shanghai First Rehabilitation Hospital, Shanghai, China.
Objectives:
Stroke is a major cause of long-term disability and cognitive impairment, substantially affecting patients' quality of life and functional independence. Effective strategies for post-stroke cognitive recovery remain limited. To evaluate the effects of transcranial magnetic stimulation (TMS) combined with reminiscence therapy on cognitive function and functional independence in stroke patients.
Methods:
A retrospective cohort study was conducted at a rehabilitation hospital from March 2017 to October 2024, including patients with ischemic stroke and cognitive impairment who received either routine treatment (n=68) or TMS combined with reminiscence therapy (n=66). Cognitive and functional outcomes were assessed using the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Trail Making Test (TMT), and Functional Independence Measure (FIM).
Results:
Post-treatment, the TMS plus reminiscence therapy group showed significantly higher MMSE (27.42 ± 3.08 vs. 25.18 ± 3.41, p=0.0001) and MoCA scores (20.05 ± 3.99 vs. 18.44 ± 4.05, p=0.0020), and shorter TMT times (65.28 ± 9.75 vs. 72.45 ± 10.32, p<0.001). FIM scores were also higher (92.18 ± 7.06 vs. 88.35 ± 7.15, p=0.0024). No significant differences in adverse events were observed.
Conclusions:
TMS combined with reminiscence therapy may effectively enhance cognitive function and functional independence in patients with post-stroke cognitive impairment.
