青年期から成人期にかけて:高次視覚野の機能的フィンガープリントは視空間処理の分化発達を明らかにする
bioRxiv : the preprint server for biology
|February 23, 2026
まとめ
青年期の脳発達は、視覚処理における継続的な可塑性を示す。集団受容野(pRF)とカテゴリー選択性は、視空間計算に影響を与えながら、青年期を通じて成熟する。
科学分野:
- 神経科学
- 発達神経科学
- 視覚神経科学
背景:
- 視空間計算は、読書、社会的相互作用、ナビゲーションに不可欠である。
- これらの計算は、カテゴリー選択的視覚野における集団受容野(pRF)に依存している。
- 青年期におけるpRFとカテゴリー選択性の発達変化は、ほとんど未解明のままである。
研究 の 目的:
- 青年期のヒト視覚野におけるpRFとカテゴリー選択性の発達軌道を調査すること。
- 異なる視覚ストリームとカテゴリーにわたる視空間計算の変動を調べること。
主な方法:
- 機能的磁気共鳴画像法(fMRI)を青年および成人参加者に適用した。
- 集団受容野(pRF)モデリングを用いて視覚野の組織を分析した。
- 腹側、外側、背側の視覚ストリームにわたるカテゴリー選択性を評価した。
主要な成果:
- カテゴリー、ストリーム、半球にわたるpRFの位置、サイズ、視野被覆率の一貫した機能的フィンガープリントが観察された。
- pRFの位置は、青年期にはほぼ成人レベルであった。
- pRFのサイズ、視野被覆率、カテゴリー選択性は、青年期から成人期にかけて、領域特異的な有意な成熟を示した。
結論:
- 青年期は、高次視覚野における機能的可塑性の継続的な重要な期間を表す。
- これらの発見は、視空間計算成熟のための発達タイムラインを提供する。
- 視覚野の組織と発達を理解するための多次元フレームワークが確立された。
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