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Updated: Feb 24, 2026

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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
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尿路閉塞性腎盂腎炎と腸球菌による菌血症:検尿異常を伴う場合
Yoshihiro Kawaguchi1, Sota Umetani2, Kazuki Nitahata3
1Department of Urology, Saiseikai Futsukaichi Hospital, Fukuoka, JPN.
Cureus
|February 23, 2026
まとめ
腸球菌(エンテロコッカス・フェカリス)による尿路閉塞性腎盂腎炎は、尿路異常を伴わずに発症することがあります。検尿結果が陰性であっても、迅速な診断と抗菌薬療法の再評価が治療成功のために不可欠です。
科学分野:
- 腎臓病学
- 感染症
- 泌尿器科学
背景:
- 尿路閉塞性腎盂腎炎の診断は、検尿結果が正常な場合、困難となることがある。
- 腸球菌(E. faecalis)は、複雑性尿路感染症や菌血症の原因となり、閉塞例では非典型的な症状を示すことがある。
研究 の 目的:
- 検尿異常を伴う尿路閉塞性腎盂腎炎の診断上の課題を強調すること。
- 検尿結果が正常であっても、この診断を考慮することの重要性を強調すること。
- 尿路ドレナージ後の持続的な発熱における抗菌薬療法の再評価の必要性を示すこと。
主な方法:
- 73歳男性の発熱と側腹部痛の症例報告。
- 初期評価には、検尿、および腸球菌(E. faecalis)陽性の血液培養が含まれた。
- 尿管結石、水腎症を示すCTスキャン、およびその後の腎盂からの尿培養により診断が確定した。
主要な成果:
- 患者は発熱と側腹部痛を呈したが、検尿は正常であった。
- 腸球菌(E. faecalis)菌血症が確認され、尿路閉塞性腎盂腎炎と診断された。
- 初期の抗菌薬療法(セフメタゾール)は、持続的な発熱のためアモキシシリン/クラブラン酸に変更され、急速な改善につながった。
結論:
- 検尿結果が陰性であっても、尿路閉塞性腎盂腎炎を疑うべきである。
- 尿路ドレナージ後の持続的な発熱は、抗菌薬療法の再評価を必要とする。
- 腸球菌(E. faecalis)は、閉塞した尿路における重症感染症の原因となり、個別化された治療が必要である。
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