股関節骨折手術後の高齢者リハビリテーション滞在期間≤4週間予測のための物理的活動および患者データを用いた機械学習アプローチ

In 2022, over 18,000 patients aged ≥70 years were hospitalized in the Netherlands for a hip fracture, with 50% requiring geriatric rehabilitation after surgery. Increasing geriatric rehabilitation patient numbers, staff shortages, and rising pressure on health care budgets make adequate care challenging. To make geriatric rehabilitation more future-proof, a stronger focus on home-based rehabilitation is needed. Early identification of patients likely to be discharged soon enables timely discharge planning and coordination of support at home. Early geriatric rehabilitation discharge planning may help organize home-based rehabilitation more effectively by arranging home care services in advance. This can facilitate smoother transitions toward home and prevent discharge delays, which is important to ensure optimal bed occupancy.

This study aims to develop machine learning (ML) models to predict a geriatric rehabilitation stay of 4 weeks or less in a skilled nursing home for older patients after hip fracture surgery, using continuously monitored physical activity data from the first week of geriatric rehabilitation and patient characteristics.

This prospective cohort study (January 2019-August 2024) included 100 patients. Patient characteristics and physical activity data from the MOX1 accelerometer (Maastricht Instruments BV) were collected during the first rehabilitation week. Principal component analysis was used to reduce the physical activity features. ML models were developed using Bayesian hyperparameter optimization and refined if necessary. The performance of the single best-performing configuration per remaining ML model type was evaluated, and the most important features for predicting the length of geriatric rehabilitation stay were identified.

Of the 3 ML models evaluated (support vector machine [SVM], ensemble of decision trees, and neural network), the SVM achieved the highest performance, with 19 out of 20 correct predictions (accuracy=0.95, 95% CI 0.85-1.00; precision=0.91, 95% CI 0.71-1.00; recall=1.00, 95% CI 1.00-1.00; F₁-score=0.95238, 95% CI 0.83-1.00; area under the curve [AUC]=0.97, 95% CI 0.83-1.00). The most important features for predicting the length of geriatric rehabilitation stay across the best-performing ML models included the continuously monitored physical activity data, time in the emergency room, functional ambulation category (FAC) at hospital discharge, age, Katz Index of Independence in Activities of Daily Living-6 (Katz-ADL6) at hospital discharge, Montreal Cognitive Assessment (MoCA), availability of nonprofessional help, surgery type, Charlson Comorbidity Index (CCI), gender, and hemoglobin level at hospital admission.

This study developed several ML models to predict a geriatric rehabilitation stay of ≤4 weeks in a skilled nursing home for older patients after hip fracture surgery. Among these models, the SVM proved to be highly accurate in its predictions with an accuracy of 0.95 (95% CI 0.85-1.00), precision of 0.91 (95% CI 0.71-1.00), recall of 1.00 (95% CI 1.00-1.00), F₁-score of 0.95 (95% CI 0.83-1.00), and AUC of 0.97 (95% CI 0.88-1.00).