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Updated: Feb 25, 2026

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
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Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE

Published on: July 29, 2014

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ウイルスの二重鎖RNAにおける端末ループ配列は,RIG-Iシグナリングを調節する.

Matthew Hackbart1, Patrick Wang1, Victoria Gnazzo1

  • 1Washington University in St Louis.

RNA (New York, N.Y.)
|February 23, 2026
PubMed
まとめ

外来RNAは,RIG-I.I.を介して先天的免疫を誘発する. この研究は,RNA幹のループが,単に5の末端ではなく,RIG-I信号伝達とインターフェロン発現を強化し,免疫刺激剤としての潜在性を示していることを明らかにしています.

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