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Updated: Feb 25, 2026

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膜に埋め込まれた極性残基は,質管理プロテアゼFtsHによって分解されるための膜タンパク質を標的とする

Michal Chai-Danino1, Noy Ravensary-Modin1, Vasiliy I Vladimirov1

  • 1Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Nature communications
|February 23, 2026
PubMed
まとめ

欠陥膜タンパク質 (MPs) は,E. coliのFtsHプロテアゼによって分解される. 露出する極性残留は,誤った折り畳みをシグナルし,分解を誘発し,膜タンパク質の完全性を維持します.

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