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Updated: Feb 25, 2026

Exploring the Arginine Methylome by Nuclear Magnetic Resonance Spectroscopy
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Published on: December 16, 2021

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ミトコンドリア内のPRMT5は,TFAMアルギニンメチレーションを通じてmtDNAの安定性を調節する

Sangheeta Bhattacharjee1, Sayan Das1, Banhi Chowdhury1

  • 1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata, India.

Nature communications
|February 23, 2026
PubMed
まとめ

タンパク質アルギニンメチルトランスフェラーゼ5 (PRMT5) は,ミトコンドリアDNA (mtDNA) の維持に不可欠です. この研究では,PRMT5がmtDNAの安定性と細胞呼吸に不可欠なTFAMを調節することを示しています.

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