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Updated: Feb 25, 2026

Study of Dendritic Cell Development by Short Hairpin RNA-Mediated Gene Knockdown in a Hematopoietic Stem and Progenitor Cell Line In vitro
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Published on: March 7, 2022

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転写因子EHFは,従来の樹状細胞の成熟と免疫抑制を促進する

Xiaoli Liu1,2,3, Ling Wang3, Yongfang Xiao3

  • 1Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Nature communications
|February 23, 2026
PubMed
まとめ

ETS同型因子 (EHF) は dendritic cell (DC) の成熟と免疫抑制を調節する. DCのEHF欠乏は,T細胞の反応を促進することによって,自己免疫疾患,感染症,腫瘍に対する抵抗性を高めます.

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A Simple and Efficient Method for Testing Immunomodulatory Agents for Generation of Tolerogenic Dendritic Cells from Human CD14+ Monocytes

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