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Updated: Feb 25, 2026

Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
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Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products

Published on: August 22, 2017

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誘導結合プラズマ質量スペクトロメトリは,フッ素検出に基づく薬物の代謝研究における定量分析のための敏感な非放射性代替品として,フッ素検出に基づいています

Sam Wouters1, Filip Cuyckens2

  • 1Preclinical Sciences & Translational Safety, Johnson & Johnson, Turnhoutseweg 30, B2340, Beerse, Belgium. SWouter1@its.jnj.com.

Analytical and bioanalytical chemistry
|February 23, 2026
PubMed
まとめ

LC-ICP-MS/MSを用いた量的なフッ素検出は,薬物の代謝研究のための新しい基準を提供します. この方法は,放射性トレーサーの必要性を回避し,薬剤開発における早期かつより正確な代謝物識別を可能にします.

キーワード:
バリウムフッ化物 (バリウムフッ化物) は,薬物の代謝 薬物の代謝人間のADMEICP-MS/MS/MSとは放射能検出器は,放射能を検出する装置です.ラジオラベルを貼った薬は,

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