高齢者の間でのイアトロゲン薬の誤用は,毒中症センターネットワークに報告されました
Hayley T Gartner1, Reeves E Simmons1, Herbert Z Wan1
1Florida/USVI Poison Information Center Jacksonville, University of Florida Health Jacksonville, Jacksonville, Florida, USA.
まとめ
高齢者におけるイアトロゲン薬の誤用は,特に投与中に,心血管薬を含むときに一般的です. 多くのエラーが害を及ぼし,緊急サービス (ED) のイベントはより高いリスクを持ち,ターゲットを絞った介入が必要になります.
科学分野:
- ゲリアトリック・メディシン (老年医学)
- 患者の安全性についてです.
- 薬理学 薬理学とは
背景:
- イアトロゲン薬の誤用は,高齢者において,予防可能な重大な害を意味する.
- これらのエラーの全範囲,種類,および結果については,依然として十分に理解されていません.
- 本研究は,緊急時および病院前の設定を含む,高齢の患者における医療関連薬剤誤りの特徴を扱っています.
研究 の 目的:
- 65歳以上の成人の医療関連のイアトロゲンな薬物誤用を記述する.
- これらの投薬エラーの設定,タイプ,結果を特定する.
- この脆弱な集団の被害を防ぐための標的型介入の情報を提供すること.
主な方法:
- 毒中症センターネットワーク (2020-2025) に報告されたイアトロゲン薬の暴露を受けた65歳以上の患者の遡及コホート研究 (2020-2025).
- 電子医療記録から抽出され,医療関連医薬品の誤差を調査したデータ.
- 誤差の重さは,National Poison Data System (NPDS) とNational Coordinating Council for Medication Error Reporting and Prevention (NCC MERP) のスケールを使用して評価され,臨床効果,薬剤,治療法は記述的に分析されました.
主要な成果:
- 182件の症例が含有基準を満たし,ほとんどの誤りは看護施設 (32%),非重症病棟 (14%),または緊急治療室 (ED) (12%) で発生しました.
- 心血管系薬剤は最も頻繁に (32%) 関与しており,誤った患者 (24%) や誤った投与量 (20%) を含む投与誤り (77%) が主な原因でした.
- 誤差の半分以上は,NCC MERP カテゴリ E 以上で,患者への害を示唆しています.
結論:
- 高齢者におけるイアトロゲン薬の誤用は,様々な介護環境で一般的であり,しばしば緊急治療室 (ED) の管理を必要とする.
- 多くのエラーが軽微な害をもたらす一方で,重大なサブセットが深刻な結果につながり,EDベースのエラーがより高いリスクを示します.
- 研究結果は,高齢者を保護するために,薬剤投与,特に心臓血管薬の投与中に標的を絞った介入の必要性を強調しています.
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