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Jianwu Zhou1, Xiaobin Deng1, Liang Peng1

  • 1National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Department of Pediatric Surgical Oncology Children's Hospital of Chongqing Medical University, Chongqing, China.

European journal of medical research
|February 24, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
ゲノムプロファイリング小児がん横紋筋肉腫軟部肉腫治療標的

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
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