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Updated: Feb 25, 2026

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「メトトレキサート誘発性認知障害におけるニューロン特異的転写調節異常：snRNA-seqによる解明」に関するコメント

Jianxin Zhou1, Yi Song

  • 1Department of Neurosurgery, Chongqing University Three Gorges Hospital, Wanzhou, Chongqing, China.

International journal of surgery (London, England)
|February 24, 2026
PubMed
まとめ

No abstract available in PubMed .

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MicroRNAs01:22

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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