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Updated: Feb 25, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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新規HLA-A*24:675アレルの次世代シーケンシングによる同定

Ruby J Siegel1, Katrin Hacke1, Rose M Ridgley1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona, USA.

HLA
|February 24, 2026
PubMed

キーワード:
HLA‐A*24:675次世代シーケンシング新規HLAアレヒトアレハイスループットヌクレオチドシーケンシングエクソンHLA-A24抗原遺伝学免疫学組織適合性試験塩基配列DNA配列解析一塩基多型配列アラインメント

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Genome-wide Association Studies-GWAS01:11

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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