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Updated: Feb 26, 2026

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食事性スルフォラファングルコシノレートは腸脳軸調節を介してストレス誘発性うつ病および脱髄を緩和する

Dan Xu1, Akifumi Eguchi2, Rumi Murayama3

  • 1Chiba University Center for Forensic Mental Health, Chiba 260-8670, Japan; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, PR China.; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, PR China.

The Journal of nutritional biochemistry
|February 24, 2026
PubMed
まとめ

食事性スルフォラファングルコシノレート（SGS）補給は、慢性ストレス下のマウスでうつ病様行動および白質損傷を予防した。SGSは腸内細菌叢と代謝物質を調節し、ストレス耐性および神経精神疾患の予防におけるその可能性を強調した。

キーワード:
慢性拘束ストレス脱髄腸内細菌叢メタボロミクススルフォラファングルコシノレート

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Sulfur Assimilation01:20

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Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
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