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血清プログラム死リガンド2は乳腺癌を有する猫で上昇する

Vitória Silva João1,2, Gonçalo Pereira1,2, Gonçalo Vicente1,3

  • 1Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, Lisbon, 1300-477, Portugal.

Scientific reports
|February 24, 2026
PubMed
まとめ

血清PD-L2（sPD-L2）は、猫の乳腺癌（FMC）の有望なバイオマーカーであり、特にHER2陽性およびトリプルネガティブサブタイプにおいて有望である。上昇したsPD-L2レベルは、FMCの診断と腫瘍特性の予測に役立ち、標的免疫療法の可能性を提供する。

キーワード:
バイオマーカー比較腫瘍学モデルELISA猫乳腺癌PD-L2

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Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...