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Updated: Feb 26, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
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性別特異的基礎代謝率とNAFLDリスク：多集団観察研究およびメンデルランダム化研究

Chunyu Hu1, Yuanling Tao1, Laixi Zhang1

  • 1Department of Health Management, The First Affiliated Hospital of Army Medical University (Southwest Hospital), Chongqing, 400038, People's Republic of China.

Diabetes, metabolic syndrome and obesity : targets and therapy
|February 25, 2026
PubMed
まとめ

基礎代謝率（BMR）が高いほど、非アルコール性脂肪性肝疾患（NAFLD）のリスク因子となる。中国集団ではBMR-NAFLD関連における性差が認められ、NAFLDの個別化された管理戦略の可能性が示唆される。

キーワード:
メンデルランダム化基礎代謝率非アルコール性脂肪性肝疾患性特異的

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Metabolic Rate01:25

Metabolic Rate

The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
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Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
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