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Updated: Feb 26, 2026

Investigations on the GaIII Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue

Investigations on the GaIII Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue

Published on: August 17, 2016

高レベル放射性廃棄物からのテクネチウム酸塩アニオンの選択的抽出のための多置換グアニジン系受容体

Uliana M Leksina¹, Vladimir A Abramov¹, Petr I Matveev¹

¹Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1 bld. 3, Moscow 119991, Russia. nenajdenko@gmail.com.

Dalton transactions (Cambridge, England : 2003)

|February 25, 2026

Abstract:

In this work, we report the design and synthesis of a novel series of guanidine-based extractants tailored for the selective and efficient extraction of the pertechnetate anion (TcO₄^-). A library of 24 structurally diverse ligands was prepared and systematically evaluated for the extraction of technetium from nitric acid solutions and high-level waste (HLW) simulants. Several compounds exhibited outstanding performance, with distribution ratios (D_Tc) exceeding 2000 and selectivity factors of up to 400 over competing anions. The extraction mechanism was investigated via back-extraction experiments, revealing the influence of nitric acid concentration, temperature, and alkaline stripping agents. The composition of the extracted species was confirmed by single-crystal X-ray diffraction (SC-XRD) and X-ray absorption spectroscopy (XAS), supporting the formation of discrete ion pairs between the guanidinium cation and pertechnetate anion. These results highlight the potential of guanidine-based receptors for targeted separation of Tc(VII) from complex nuclear waste matrices.

キーワード:

グアニジン抽出剤テクネチウム酸塩核廃棄物分離

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