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Updated: Feb 26, 2026

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Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
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緑内障および緑内障疑いにおける頸動脈ドップラー画像検査
Nidhi Mamtani1, Mani Baskaran, Trupti S Patil
1Smt. Jadhavbai Nathmal Singhvee Glaucoma Services, Sankara Nethralaya Medical Research Foundation, Chennai, Tamil Nadu, India.
Indian journal of ophthalmology
|February 25, 2026
まとめ
頸動脈閉塞性疾患(COD)は緑内障疑いではまれであるが、説明不能な視野進行を伴う正常眼圧緑内障(NTG)および原発開放隅角緑内障(POAG)患者ではより頻繁に見られ、これらの特定のグループにおいて臨床的関連性を示唆している。
科学分野:
- 眼科学
- 血管神経学
- 医用画像処理
背景:
- 緑内障は世界的に不可逆的な失明の主な原因である。
- 頸動脈閉塞性疾患(COD)は脳血管イベントの重要な危険因子である。
- 緑内障とCODの関係はさらなる調査が必要である。
研究 の 目的:
- 頸動脈閉塞性疾患(COD)と緑内障との関連性を決定すること。
- 緑内障疑い、原発開放隅角緑内障(POAG)、および正常眼圧緑内障(NTG)におけるCODの有病率を評価すること。
主な方法:
- 2012年1月から2022年6月までの間に279人の患者(485眼)のカルテと頸動脈ドップラーレポートの遡及的レビュー。
- 適格基準:緑内障疑い、血管病変疑いまたは説明不能なハンフリー視野(HVF)進行を伴うPOAG、またはNTG。
- 頸動脈関与は、ドップラー画像検査における有意な狭窄によって定義された。
主要な成果:
- POAGの7.4%、NTGの11.4%、説明不能なHV F進行を伴う患者の12%で頸動脈狭窄が観察された。
- 緑内障疑いのわずか3%に10%を超える狭窄が見られた(P > 0.05)。
- 視野指数(VFI)の悪化と狭窄の増加との間に弱い負の相関(r = -0.22)が見られた。
結論:
- 緑内障疑いにおける頸動脈閉塞性疾患(COD)はまれである。
- CODは、説明不能な視野進行を経験しているNTGおよびPOAG患者においてより一般的である。
- CODは、主にこれらの特定の緑内障サブグループ内で臨床的意義を持つ可能性がある。
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