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Updated: May 6, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

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KAT8ノックアウトマウスの作製プロトコルおよび4NQO誘発食道癌モデルへの応用

Dandan Zhang1, Ming Jiang2, Kangdong Liu3

  • 1China-US (Henan) Hormel Cancer Institute, No. 127, Zhengzhou, Henan 450000, China; Institute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.

STAR protocols
|February 25, 2026
PubMed
まとめ

No abstract available in PubMed .

キーワード:
バイオテクノロジーと生物工学CRISPR癌モデル生物

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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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