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Updated: Feb 28, 2026

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説明不能な習慣性流産におけるVδ2 T細胞の細胞傷害性分極シフトと血管機能障害の関連性：予備的研究

Xiao-Xia He1, Hong-Xing Li1, Yi Jin2

  • 1The First School of Clinical Medicine, Lanzhou University, Lanzhou 730000, China; Clinical Medical Research Center for Reproductive Diseases of Gansu Province, Lanzhou 730000, China; Department of Hematology, The First Hospital of Lanzhou University, Lanzhou 730000, China.

Journal of reproductive immunology
|February 25, 2026
PubMed
まとめ

説明不能な習慣性流産（URM）は、細胞傷害性Vδ2 γδT細胞および血管障害マーカーと関連している。グランザイムB陽性ペルフォリン陽性Vδ2細胞の増加は、血管損傷の増加と相関し、URMにおける新たな免疫血管相互作用を示唆している。

キーワード:
細胞傷害性顆粒フローサイトメトリー説明不能な習慣性流産（URM）血管内皮機能障害γδT細胞（Vδ2サブセット）

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