関連する実験動画

Updated: Feb 28, 2026

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

SPECT/CT骨シンチグラフィーにおける診断品質を維持しながら放射線線量を低減するためのCTパラメータの最適化

Manal Alezzi¹, Owais Kotbi², Gihad Hammid³

¹Department of Medical Physics, King Abdullah Medical City, Makkah, Saudi Arabia.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

|February 25, 2026

要旨

Background:

Minimizing patient radiation exposure while maintaining diagnostic accuracy is essential in hybrid imaging modalities such as SPECT/CT. This study aimed to develop and validate a reduced-dose CT protocol for bone SPECT/CT imaging by optimizing CT acquisition parameters to lower radiation exposure without compromising image quality.

Methods:

A two-part study was performed. The first part was a phantom study using a Jaszczak model, which evaluated multiple CT current and slice thickness combinations to identify the optimal image quality with minimized radiation dose. The second part was a clinical trial conducted to compare 20 patients scanned using the optimized protocol (40 mA) with 40 patients previously scanned using the standard protocol (60 mA) as historical controls. The SPECT parameters remained unchanged. Quantitative metrics (CR, COV, SNR, and CTDIvol) and blinded qualitative assessments were used.

Results:

The optimized CT protocol reduced patient dose (median CTDIvol: 3.04 vs. 4.08 mGy, p < 0.001) without statistically significant differences in SPECT image quality (median Likert score: 3 in both groups) or diagnostic metrics.

Conclusion:

The proposed 40 mA CT protocol reduces radiation dose in bone SPECT/CT imaging while preserving diagnostic confidence and is suitable for clinical implementation.

キーワード:

骨シンチグラフィー画質プロトコル最適化放射線線量低減 SPECT/CT

さらに関連する動画

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT

A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT

Published on: June 12, 2020

関連する概念動画

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Radiological Investigation I: X-ray and CT

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Imaging Studies I: CT and MRI

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

X-ray Imaging

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...