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Updated: Jun 21, 2026

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
11:12

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Published on: August 1, 2018

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骨髄ニッチにおける神経芽腫細胞クローン活動の不均一性を動的に検出するマルチプレックスバイオマーカー

Anna M Schroeer1, Annika Winkler1, Marion Fillies1

  • 1Department of Pediatric Oncology and Hematology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Berlin, 13353 Berlin, Germany.

Cancer letters
|February 25, 2026
PubMed
まとめ

本研究では、神経芽腫のモニタリングのためのマルチプレックスバイオマーカー検出を導入し、最小残存疾患（MRD）検出の精度を向上させる。この方法は多様な腫瘍クローンを捉え、再発予測と治療モニタリングの改善に役立つ。

キーワード:
MP-PCRMRDMYCNバイオマーカー小児がん個別化医療

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Bone Marrow Sampling and Transplants01:22

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...