ヘマトゥリアはワルファリンだけではない：ラムダ優位のIgA腎症

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Updated: Feb 28, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

Benny Chia Wue Lim¹, Fauzah Binti Abd Ghani², Fuah Kar Wah¹

¹Department of Nephrology, Hospital Sultan Idris Shah, Serdang, Malaysia.

BMJ case reports

|February 25, 2026

Abstract:

A woman in her 20s with a mechanical mitral valve replacement on long-term warfarin therapy presented with frank haematuria and acute kidney injury (AKI). The initial clinical impression was anticoagulant-related nephropathy. However, due to the persistence of urinary abnormalities, further evaluation was undertaken. Renal biopsy revealed immunoglobulin A nephropathy with lambda light chain predominance, raising concern for an underlying monoclonal gammopathy. The patient was managed conservatively with antiproteinuric therapy alone, without immunosuppression, and demonstrated favourable renal recovery. This case highlights the diagnostic importance of renal biopsy and thorough clinical reassessment in patients with haematuria and AKI, particularly in the context of anticoagulation.

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急性腎不全慢性腎不全ネフローゼ症候群

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Detection of MicroRNA Expression in the Kidneys of Immunoglobulin A Nephropathic Mice

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Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

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