ローディング前の早期X線骨吸収がインプラント関連転帰に及ぼす影響：長期後ろ向き研究

This retrospective study primarily evaluated whether early radiographic bone loss (ERBL) predicts progressive bone loss (PBL), and secondarily assessed its association with implant survival and peri-implant diseases.

Adults with dental implants who were followed for at least 5 years were included. Implants presenting ERBL, defined as apical migration of the interproximal marginal bone involving exposure of the implant rough surface before insertion of the final prosthesis, were classified as ERBL+; non-exposure group was defined as implants without evidence of ERBL (ERBL-). Regression analyses were performed to evaluate associations with PBL.

A total of 259 implants, 87 ERBL+, and 172 ERBL- were included. Mean follow-up periods were 8.8 ± 3.0 years for the ERBL+ and 11.5 ± 1.7 years for the ERBL-. ERBL+ exhibited significantly greater PBL than ERBL- (-1.6 ± 1.0 mm to -2.3 ± 1.7 mm vs. -0.4 ± 1.2 mm to -0.5 ± 1.2 mm; p < 0.001). Implant survival was lower in ERBL+ (67.8%) compared with ERBL- (98.3%; p < 0.001). Peri-implantitis was diagnosed in 63.2% of implants in the ERBL- group versus 5.2% in ERBL- (p < 0.001), and 68.4% of patients versus 6.1% of ERBL- (p < 0.001). ERBL was the strongest predictor of greater PBL (+1.46 mm; p < 0.0001). Male sex (+0.40 mm; p = 0.02), smoking (+0.61 mm; p = 0.004), each additional implant (+0.17 mm; p < 0.0001), single-crown restorations (+0.66 mm; p = 0.005), and bone-level implants (+0.32 mm; p = 0.005) were associated with increased PBL.

ERBL is a strong predictor of PBL and is associated with a higher risk of implant loss and peri-implantitis onset.