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Updated: Feb 28, 2026

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

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大気汚染減衰とAECOPD入院との関係の変化：石家荘、中国、2017-2024年の厳格な管理期間中

Jingsi Cao¹, Zihan Ren², Xinyue Liu¹

¹The First Department of Pulmonary and Critical Care Medicine, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Respiratory Critical Care Medicine, Hebei Institute of Respiratory Diseases, Shijiazhuang, Hebei, China.

Frontiers in public health

|February 26, 2026

要旨

Background:

Shijiazhuang, a typical industrial city, faced severe air pollution that elevated AECOPD risk. The period 2017-2024 coincided with stringent air pollution control, providing a key window to examine the evolving relationship between air quality improvements and AECOPD hospitalizations.

Methods:

We analyzed 57,782 AECOPD hospitalizations (2017-2024) and air pollution data using a generalized additive Poisson time-series model. The analysis incorporated distributed lag non-linear terms while adjusting for meteorological conditions, seasonal trends, and day-of-week effects, with sensitivity analyses confirming result reliability.

Results:

PM_2.5, PM10, and SO₂ concentrations fell by 46%, 68%, and 85%, respectively. PM_2.5-attributable excess cases under WHO standards dropped by 37.1%. Crucially, the association strength (relative risk) between most pollutants and hospitalizations showed a significant attenuating trend over time.

Conclusion:

During this stringent air pollution control period in Shijiazhuang, marked air quality improvements were associated with reduced AECOPD hospitalizations and attenuated pollutant-health associations. Persistent ozone pollution highlights the need for coordinated VOC-NO^x management.

キーワード:

AECOPD入院大気汚染管理生態学的研究呼吸器系への健康影響時系列分析

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