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Updated: Feb 28, 2026

Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
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Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method

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レンティヌラ・エドデス抽出物の人工知能支援最適化による生理活性プロファイルと治療的可能性の向上

Mustafa Sevindik1, Vadim Tagirovich Khassanov2, Ayşenur Gürgen3

  • 1Department of Biology, Faculty of Engineering and Natural Sciences, Osmaniye Korkut Ata University, 80000, Osmaniye, Türkiye. sevindik27@gmail.com.

Scientific reports
|February 26, 2026
PubMed
まとめ

人工知能（AI）を用いた人工ニューラルネットワーク-遺伝子アルゴリズム（ANN-GA）モデルによる最適化は、応答曲面法（RSM）と比較してレンティヌラ・エドデス（シイタケ）抽出物の生物活性を大幅に向上させた。このAIアプローチは、抗酸化作用、抗コリンエステラーゼ作用、抗増殖作用を強化する。

キーワード:
抗コリンエステラーゼ活性抗酸化活性抗増殖効果人工ニューラルネットワーク–遺伝子アルゴリズム抽出最適化フェノール化合物応答曲面法

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Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...
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