Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Long-term Depression01:03

Long-term Depression

3.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.5K
Long-term Depression01:05

Long-term Depression

33.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.5K
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

1.1K
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.1K
Neuroplasticity01:01

Neuroplasticity

2.1K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.1K
High-Level and Low-Level Awareness01:19

High-Level and Low-Level Awareness

815
Controlled processes in human consciousness represent high-alert mental states where individuals deliberately focus their attention on achieving specific goals. Controlled processes can be seen in situations like mastering new technology, where a person might become so absorbed that they ignore surrounding distractions. Such processes involve selective attention, requiring one to concentrate on particular elements of experience while disregarding others. These are governed by executive...
815
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

2.8K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
2.8K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Glutamatergic signaling underlies brain structural organization for mathematical and reading abilities in children.

Nature communications·2026
Same author

Temporally-resolved deep learning reveals autism symptom-specific neural signatures during naturalistic social experiences.

Research square·2026
Same author

Nonergodicity and Simpson's paradox in neurocognitive dynamics of cognitive control.

Nature communications·2026
Same author

Latent brain state dynamics predict early amyloid accumulation and cognitive impairment.

bioRxiv : the preprint server for biology·2026
Same author

Recurrent neural network models reveal unified mechanisms generating event-related potentials from MMN to P300.

bioRxiv : the preprint server for biology·2025
Same author

Neurodevelopmental commonalities in cognitive control networks for mathematics and reading in meta-analysis of 3308 participants.

Nature communications·2025
Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026
Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026
Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026
Same journal

When does additional information improve accuracy of RNA secondary structure prediction?

bioRxiv : the preprint server for biology·2026
Same journal

Normative brain-state trajectories reveal deviation from healthy aging in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026
Same journal

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026
関連記事をすべて見る

関連する実験動画

Updated: Feb 28, 2026

Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network
11:02

Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network

Published on: December 28, 2010

13.5K

デフォルトモードネットワーク機能および機能不全の生物物理学的メカニズム

Trang-Anh E Nghiem, Vinod Menon

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    まとめ
    この要約は機械生成です。

    脳シミュレーションは、島皮質がデフォルトモードネットワーク（DMN）をどのように抑制するか、また興奮性/抑制性バランスの乱れが脳疾患におけるDMN機能不全をどのように引き起こすかを明らかにします。この研究は、細胞メカニズムと大規模ネットワークダイナミクスを関連付けます。

    キーワード:
    デフォルトモードネットワーク計算神経科学神経科学システム神経科学興奮性-抑制性バランス

    さらに関連する動画

    Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
    12:09

    Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

    Published on: August 5, 2014

    18.6K
    Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
    10:43

    Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

    Published on: July 1, 2014

    15.9K

    関連する実験動画

    Last Updated: Feb 28, 2026

    Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network
    11:02

    Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network

    Published on: December 28, 2010

    13.5K
    Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
    12:09

    Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

    Published on: August 5, 2014

    18.6K
    Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
    10:43

    Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

    Published on: July 1, 2014

    15.9K

    科学分野:

    • 神経科学
    • 計算神経科学
    • システム神経科学

    背景:

    • デフォルトモードネットワーク（DMN）は内部認知に不可欠ですが、外部刺激によるその抑制は細胞レベルではほとんど理解されていません。
    • DMNの機能不全は、神経興奮と抑制のバランスの乱れと関連していることが多く、さまざまな脳疾患に関連しています。

    主な方法:

    • 神経生物物理学を組み込んだ全脳計算モデリング。
    • 逆行性トレーサー由来の方向性マウス脳コネクトミクスの統合。
    • ネットワークダイナミクスの体系的な脳全体の分析とパラメータ空間の探索。

    結論:

    • この研究は、細胞レベルの興奮性/抑制性バランスとDMNの堅牢性および脆弱性との関連メカニズムを提供します。
    • この発見は、DMN抑制における島皮質の重要な役割を強調し、味覚後帯状皮質などの特定の調節ハブを脆弱なポイントとして特定します。
    • このモデルは、脳疾患で見られるDMN機能不全の不均一なパターンに関する洞察を提供し、潜在的な治療標的を示唆しています。