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Updated: Feb 28, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

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細胞内自己抗体が引き起こす自己免疫のメカニズムを明らかにする空間的トランスクリプトミクス解析

Iago Pinal-Fernandez, Katherine Pak, Maria Casal-Dominguez

    medRxiv : the preprint server for health sciences
    |February 27, 2026
    PubMed
    まとめ

    自己抗体の細胞内への取り込みは、自己免疫疾患における重要な病態メカニズムである。本研究は、それが複数の病態にわたる疾患特異的なトランスクリプトーム変化と炎症を駆動することを示し、病原性メカニズムの統一的枠組みを提供する。

    キーワード:
    自己抗体自己免疫疾患トランスクリプトミクス炎症細胞内取り込み

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