Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

1.1K
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.1K
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

3.2K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
3.2K
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

1.0K
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
1.0K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

336
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
336
Adrenergic Agonists: Indirect-Acting Agents01:25

Adrenergic Agonists: Indirect-Acting Agents

2.9K
Indirect-acting adrenergic agonists potentiate the effects of endogenous catecholamines through different mechanisms without directly binding to adrenoceptors.
One mechanism involves depleting stored catecholamines by displacing them from synaptic vesicles. These agents, known as "displacers," are transported into vesicles at the expense of noradrenaline. Examples include amphetamine and tyramine, which lack a catechol moiety, resulting in prolonged action, improved oral...
2.9K
Adrenergic Agonists: Mixed-Action Agents01:28

Adrenergic Agonists: Mixed-Action Agents

1.6K
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate adrenoceptors and indirectly release stored neurotransmitters, amplifying the adrenergic response.
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
1.6K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Clarifying Recurrence, Bleeding Risk, and Procedural Burden in Central Renal Tumor Ablation.

Journal of vascular and interventional radiology : JVIR·2026
Same author

Explanation-Guided Reconstruction of Missing Clinical Features for Survival Prediction in Pancreatic Cancer.

IEEE journal of biomedical and health informatics·2026
Same author

Comment on: Percutaneous Cryoablation of Clinical T1b Renal Tumors: A Tertiary Cancer Center Experience.

Cardiovascular and interventional radiology·2026
Same author

Improved pancreatic imaging with photon-counting CT: a retrospective comparison with conventional CT.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same author

Iceball Margin < 5 mm Is Associated with Local Failure after CT-Guided Cryoablation of cT1a Renal Cell Carcinoma.

Journal of vascular and interventional radiology : JVIR·2026
Same author

Image-guided percutaneous ablation techniques for the treatment of renal cell carcinoma: a primer for radiologists.

Abdominal radiology (New York)·2026

関連する実験動画

Updated: Feb 28, 2026

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

16.8K

中枢刺激薬でADHD治療を受けている小児および青年における投薬休止の影響

Solveig Kärk Abildtrup Larsen1,2, Maja Sundahl Wilkinson1,2, Krista Dybtved Kjærgaardrhus3

  • 1Røntgen og Skanning, Aarhus Universitetshospital.

Ugeskrift for laeger
|February 27, 2026
PubMed
まとめ

投薬休止は、体重減少、不眠症、または耐性を経験している患者に利益をもたらす可能性があります。効果的な実施のためには、明確なガイドラインの開発が不可欠です。

キーワード:
投薬休止ADHD中枢刺激薬小児青年体重減少不眠症耐性

さらに関連する動画

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

6.5K
Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
13:09

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

11.1K

関連する実験動画

Last Updated: Feb 28, 2026

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

16.8K
The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

6.5K
Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
13:09

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

11.1K

科学分野:

  • 薬理学
  • 臨床医学
  • 患者ケア

背景:

  • 投薬休止は、投薬の中断期間です。
  • その適用には、患者固有の要因を慎重に考慮する必要があります。
  • 既存の文献は潜在的な利点を強調していますが、包括的なガイドラインが不足しています。

研究 の 目的:

  • 投薬休止の関連性と適用をレビューすること。
  • 投薬休止から利益を得る可能性のある患者集団を特定すること。
  • さらなる研究とガイドライン開発の必要性を強調すること。

主な方法:

  • 投薬休止に関する既存の研究の文献レビュー。
  • 投薬休止が考慮される患者の症例と状態の分析。
  • 潜在的なガイドラインを知らせるための調査結果の統合。

主要な成果:

  • 投薬休止は、体重減少、BMIの低下、不眠症、または後天的な耐性を経験している患者に関連があります。
  • 青年は、治療の理解と責任感を育むために、投薬休止から利益を得る可能性があります。
  • このレビューは、医療専門家、保護者、患者のための具体的なガイドラインの必要性を強調しています。

結論:

  • 投薬休止は、特定の患者グループに治療の可能性を提供します。
  • 投薬休止プロトコルを最適化するには、さらなる研究が不可欠です。
  • 安全かつ効果的な使用のためには、明確でエビデンスに基づいたガイドラインの開発が重要です。