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Updated: Mar 1, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

多尿・多飲症候群の診断アップデート

Al-Zada Al Aguilar¹, Wen Liu², Deanna Bilotti³

¹Al-Zada "Al" Aguilar is Acute Care Nurse Practitoner, MICU Advanced Practice Provider Service, and Team Member, APP Fellowship Program, Robert Wood Johnson University Hospital, 1 Robert Wood Johnson Place, New Brunswick, NJ 08901 (al-zada.aguilar2@rwjbh.org); and Adjunct Clinical Faculty, Rutgers University, School of Nursing, Division of Advanced Nursing Practice, Post-Baccalaureate DNP AGACNP Program, New Brunswick, New Jersey.

AACN advanced critical care

|February 27, 2026

Abstract:

Polyuria-polydipsia syndromes are rare disorders characterized by hypotonic polyuria and polydipsia. They may result from complete or partial arginine vasopressin deficiency or resistance or may take the secondary form of primary polydipsia. Traditional diagnostic tests have limitations, making differentiation from other polyuric disorders challenging. New assays and updated algorithms have enhanced diagnostic accuracy and efficiency. This article reviews the pathophysiology, diagnostic challenges, and latest advancements associated with polyuria-polydipsia syndromes. As patients' conditions become more complex, staying up to date with evolving diagnostic algorithms is essential to safe, high-quality, and evidence-supported care.

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アルゴリズム多尿・多飲症候群検査アップデート

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