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てんかん発作部位特定手法のエコシステム構築：ニューラル脆弱性を第一歩として

Jiefei Wang1, Anne-Cecile Lesage2, Oliver Zhou2

  • 1Department of Biostatistics & Data Science, University of Texas Medical Branch, Galveston, TX, USA.

eNeuro
|February 27, 2026
PubMed
まとめ

この研究では、薬剤耐性てんかんにおける発作焦点地帯（SOZ）を特定するための計算手法を標準化・共有する3つのRパッケージ（TableContainer、Epoch、EZFragility）を紹介する。オープンソースフレームワークは、発作部位特定アルゴリズム開発における再現性と協調性を高める。

キーワード:
てんかん発作焦点地帯iEEGRパッケージ計算神経科学再現性オープンソース

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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